An automatic titrator is a precision analytical instrument widely used in chemical, pharmaceutical, food, environmental and academic laboratories. Its core function is to determine the concentration of a target substance by accurately controlling titrant addition and detecting the reaction endpoint.
The working principle of an automatic titrator is based on controlled volumetric titration combined with high-precision sensors. During operation, the instrument adds titrant step by step through a motor-driven burette while continuously monitoring changes in potential, pH, conductivity or color, depending on the selected detection method. Once the system detects a sharp change that corresponds to the equivalence point, the titration automatically stops and calculates the result.
Modern automatic titrators from Nanbei Instrument integrate intelligent control systems, digital signal processing and advanced electrodes to ensure excellent repeatability and high accuracy. Data can be stored, exported or connected to laboratory information management systems for further analysis. For more details about product configurations, visit our automatic titrator solutions page.
Although automatic titrators significantly reduce human error, correct operation remains essential for reliable results. Before starting a titration, users should ensure that all glassware, tubing and electrodes are clean and free from contamination. Residual chemicals may directly affect endpoint detection and calculation accuracy.
Electrode calibration is another critical precaution. pH or potential electrodes must be calibrated regularly using standard buffer solutions. Temperature variations should also be considered, as they may influence reaction kinetics and electrode response. Always allow the instrument and samples to reach a stable ambient temperature before testing.
In addition, the selection of titration mode, titrant concentration and stirring speed should match the sample characteristics. Excessive stirring can introduce air bubbles, while insufficient mixing may lead to delayed endpoint detection. Following the operating guidelines provided by Nanbei Instrument helps extend instrument lifespan and maintain stable performance.

In daily laboratory use, users may encounter issues such as unstable endpoints, inconsistent results or slow titration speed. These problems are often related to electrode aging, air bubbles in the burette, or incorrect parameter settings. Replacing worn electrodes and properly degassing the titrant usually resolves signal instability.
For complex samples with weak reaction signals, advanced titration modes such as dynamic titration or multi-endpoint analysis are recommended. Nanbei Instrument automatic titrators support flexible method customization, allowing users to optimize detection sensitivity and improve analytical efficiency.
When laboratories require long-term stable operation and technical support, choosing a reliable supplier is crucial. Nanbei Instrument provides not only high-quality automatic titrators, but also complete application solutions and professional after-sales service. You can explore related laboratory instruments through our laboratory instruments center to build an integrated analytical workflow.